易曉明 彭小娜

摘要：目的? 探討氧氣驅(qū)動霧化吸入對支氣管哮喘患者肺功能及血氧飽和度的影響。方法? 選取2017年3月～2019年3月我院收治的86例支氣管哮喘患者，按照隨機(jī)數(shù)字表法分為對照組和觀察組，各43例。對照組實施超聲霧化吸入治療，觀察組實施氧氣驅(qū)動霧化吸入治療，比較兩組肺功能指標(biāo)（PA-aDO2、FEV1、PEF及RI）、血氧飽和度及不良反應(yīng)發(fā)生率。結(jié)果? 治療后，觀察組PA-aDO2、RI低于對照組[（2.40±0.39）kPa vs（2.97±0.42）kPa]、[（0.18±0.08）vs（0.29±0.06）]，F(xiàn)EV1、PEF高于對照組[（2.01±0.16）L vs（1.46±0.18）L]、[（125.29±9.68）ml/min vs（108.55±8.79）ml/min]，差異有統(tǒng)計學(xué)意義（P<0.05）。觀察組血氧飽和度高于對照組[（95.04±2.53）% vs（88.63±2.42）%]，差異有統(tǒng)計學(xué)意義（P<0.05）。兩組不良反應(yīng)發(fā)生率比較（6.98% vs 11.63%），差異無統(tǒng)計學(xué)意義（P>0.05）。結(jié)論? 氧氣驅(qū)動霧化吸入可有效增強(qiáng)支氣管哮喘患者肺功能，提高血氧飽和度，且不增加不良反應(yīng)。

關(guān)鍵詞：支氣管哮喘;氧氣驅(qū)動霧化吸入;肺功能;血氧飽和度

中圖分類號：R725.6? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?文獻(xiàn)標(biāo)識碼：A? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?DOI：10.3969/j.issn.1006-1959.2019.23.030

文章編號：1006-1959（2019）23-0110-03

Effect of Oxygen-Driven Aerosol Inhalation on Lung Function and

Oxygen Saturation in Patients with Bronchial Asthma

YI Xiao-ming1，PENG Xiao-na2

（Department of Internal Medicine，Subject Two1，Department of Respiratory Medicine2，the Second People's Hospital of Yichun City，Yichun 336000，Jiangxi，China）

Abstract：Objective? To investigate the effects of oxygen-driven aerosol inhalation on lung function and oxygen saturation in patients with bronchial asthma. Methods? 86 patients with bronchial asthma admitted to our hospital from March 2017 to March 2019 were randomly divided into the control group and the observation group， 43 cases each. Ultrasonic nebulization inhalation was performed in the control group， and oxygen-driven nebulization inhalation was performed in the observation group. The lung function indexes （PA-aDO2， FEV1， PEF and RI）， blood oxygen saturation and adverse reaction rate were compared between the two groups.Results? After treatment， the observation group PA-aDO2， RI was lower than the control group [（2.40±0.39） kPa vs （2.97±0.42） kPa]， [（0.18±0.08） vs （0.29±0.06）]， FEV1， PEF was higher than the control group [（2.01±0.16） L vs （1.46±0.18） L]， [（125.29±9.68） ml/min vs （108.55±8.79） ml/min]， the difference was statistically significant （P<0.05）. The oxygen saturation of the observation group was higher than that of the control group [（95.04±2.53）% vs （88.63±2.42）%]， the difference was statistically significant （P<0.05）. The incidence of adverse reactions was compared between the two groups （6.98% vs 11.63%），the difference was not statistically significant （P>0.05）.Conclusion? Oxygen-driven aerosol inhalation can effectively enhance lung function and improve oxygen saturation in patients with bronchial asthma without increasing adverse reactions.