梅菊香?周泉華?尹永勝?徐向楊?吳范?趙娟
[摘要] 目的 探討和分析在婦科腹腔鏡手術(shù)麻醉中應(yīng)用靶控輸注枸櫞酸芬太尼或瑞芬太尼的臨床療效及價(jià)值。 方法 選取2013年2~12月在我院接受婦科腹腔鏡手術(shù)治療的患者90例為研究對象,隨機(jī)分成A組和B組,A組采取異丙酚復(fù)合靶濃度1.5ng/mL枸櫞酸芬太尼進(jìn)行手術(shù)麻醉,B組采取異丙酚復(fù)合靶濃度4.0ng/mL瑞芬太尼進(jìn)行手術(shù)麻醉,其中異丙酚靶濃度均為3ug/mL;觀察和對比兩組SBP(收縮壓)、SDP(舒張壓)和HR(心率)的變化等情況。 結(jié)果 麻醉后,B組的SBP(收縮壓)、SDP(舒張壓)和HR(心率)的變化等情況顯著好于A組,差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。 結(jié)論 在婦科腹腔鏡手術(shù)中應(yīng)用靶控輸注枸櫞酸芬太尼進(jìn)行麻醉,其血流動(dòng)力學(xué)更加穩(wěn)定,但蘇醒時(shí)間會(huì)慢于瑞芬太尼,瑞芬太尼麻醉后給予鎮(zhèn)痛時(shí)間會(huì)提前,臨床醫(yī)師需注意。
[關(guān)鍵詞] 腹腔鏡手術(shù);靶控輸注;枸櫞酸芬太尼;瑞芬太尼;麻醉
[中圖分類號(hào)] R614.24 [文獻(xiàn)標(biāo)識(shí)碼] B [文章編號(hào)] 2095-0616(2015)02-82-03
Clinical studies on target-controlled infusion of fentanyl citrate or remifentanil anesthesia for laparoscopic surgery in gynecology
MEI Juxiang ZHOU Quanhua YIN Yongsheng XU Xiangyang WU Fan ZHAO Juan
Qidong People's Hospital, Qidong 226200, China
[Abstract] Objective To investigate and analysis the clinical effects and value of target-controlled infusion of fentanyl citrate or remifentanil application in gynecological laparoscopic surgery. Methods Selected 90 patients after laparoscopic surgical treatment in our hospital as the object of study, and randomly divided them into group A and group B, group A took composite target propofol concentration 1.5ng/mL citrate fentanyl on anesthesia, group B take composite target propofol concentration 4.0ng/mL remifentanil on anesthesia, target concentration of two groups propofol were 3ug/mL; Observed and compared the changes on SBP(systolic pressure), the SDP(diastolic pressure) and so on of two groups. Results After anesthesia, SBP(systolic blood pressure), SDP(DBP) and HR(heart rate) changes of B group were significantly better than A group, with statistical difference(P<0.05). Conclusion The application of fentanyl citrate target controlled infusion in gynecological laparoscopic surgery anesthesia, has more stable hemodynamics, however awakening time is slower than remifentanil, remifentanil will give analgesic time after anesthesia ahead of time, which clinicians should pay attention to.
[Key words] Laparoscopic surgery; Target controlled infusion; Fentanyl citrate; Remifentanil; Anesthesia
隨著醫(yī)療水平的不斷發(fā)展,腹腔鏡技術(shù)的不斷成熟,其在婦科手術(shù)過程中應(yīng)用的頻率越來越高[1-2]。因?yàn)榇朔N手術(shù)對患者的創(chuàng)傷較小,傳統(tǒng)手術(shù)的麻醉方法可能不再適應(yīng)。因此此種手術(shù)相適應(yīng)的麻醉方法,也是我們要重點(diǎn)研究的問題[3]。為分析在腹腔鏡手術(shù)中應(yīng)用靶控輸注枸櫞酸芬太尼或瑞芬太尼的臨床效果,選取在我院接受該類手術(shù)的患者90例為研究對象,隨機(jī)分為兩組,分別采取上述兩種藥物復(fù)合丙泊酚實(shí)施手術(shù)麻醉,現(xiàn)將結(jié)果整理報(bào)道如下。
1 資料與方法
1.1 一般資料
選取2013年2~12月在我院接受婦科腹腔鏡手術(shù)治療的患者90例為研究對象,年齡21~57歲,ASA分級(jí)Ⅰ~Ⅱ級(jí);將上述選取對象隨機(jī)分成A組和B組,每組45例,兩組在年齡、手術(shù)方式等一般資料差異無統(tǒng)計(jì)學(xué)意義,具有可比性。本研究選取對象病癥為宮外孕、卵巢腫瘤等疾病。
1.2 麻醉方法
本研究兩組對象行婦科腹腔鏡手術(shù)均由同一組醫(yī)師完成,術(shù)前均不給藥。入室后,及時(shí)行血壓、endprint