亚洲免费av电影一区二区三区,日韩爱爱视频,51精品视频一区二区三区,91视频爱爱,日韩欧美在线播放视频,中文字幕少妇AV,亚洲电影中文字幕,久久久久亚洲av成人网址,久久综合视频网站,国产在线不卡免费播放

        ?

        Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

        2021-01-07 23:21:09RominaLibsteretal
        四川生理科學(xué)雜志 2021年1期

        Romina Libster, et al.

        Background: Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive.Among them, convalescent plasma administered to hospitalized patients has been unsuccessful, perhaps because antibodies should be administered earlier in the course of illness.

        Methods: We conducted a randomized, double-blind, placebo-controlled trial of convalescent plasma with high IgG titers against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in older adult patients within 72 hours after the onset of mild Covid-19 symptoms.The primary end point was severe respiratory disease, defined as a respiratory rate of 30 breaths per minute or more, an oxygen saturation of less than 93% while the patient was breathing ambient air, or both.The trial was stopped early at 76% of its projected sample size because cases of Covid-19 in the trial region decreased considerably and steady enrollment of trial patients became virtually impossible.

        Results: A total of 160 patients underwent randomization.In the intention-to-treat population, severe respiratory disease developed in 13 of 80 patients (16%) who received convalescent plasma and 25 of 80 patients (31%) who received placebo(relative risk, 0.52; 95% confidence interval [CI], 0.29 to 0.94; P = 0.03), with a relative risk reduction of 48%.A modified intention-to-treat analysis that excluded 6 patients who had a primary end-point event before infusion of convalescent plasma or placebo showed a larger effect size (relative risk, 0.40; 95% CI, 0.20 to 0.81).No solicited adverse events were observed.

        Conclusions: Early administration of high-titer convalescent plasma against SARS-CoV-2 to mildly ill infected older adults reduced the progression of Covid-19.

        亚洲av日韩av高潮潮喷无码 | 欧美日韩在线视频一区| 亚洲一区二区三区内裤视| 久久成人影院精品777| 中文字幕精品久久久久人妻红杏ⅰ| 欲求不満の人妻松下纱荣子 | 人妻少妇一区二区三区| 极品粉嫩小仙女高潮喷水视频| 久久久成人av毛片免费观看| 亚洲国产精品久久又爽av| 人妻少妇乱子伦精品| 日韩久久一级毛片| 国产亚洲欧美在线播放网站| 亚洲色图在线视频观看| 亚洲综合偷自成人网第页色| 国产xxxxx在线观看| 亚洲无毛片| 日韩国产有码精品一区二在线| 久久精品国产亚洲av网站| 亚洲av无码一区东京热| 伊人久久大香线蕉亚洲五月天| 久久人人爽人人爽人人av东京热| 亚洲色www无码| 中文字幕一区二区在线| 一区二区三区视频亚洲| 伊人久久大香线蕉午夜av | 91乱码亚洲精品中文字幕| 久久狠狠爱亚洲综合影院| 欧美金发尤物大战黑人| 久久久久久久妓女精品免费影院| av男人的天堂第三区| 变态另类手机版av天堂看网| 最近中文字幕完整版免费 | 日本不卡一区二区高清中文| 天堂网av在线免费看| 国产精品女老熟女一区二区久久夜 | 国产人成精品免费久久久| 精品亚洲成a人无码成a在线观看| 波多野结衣乳巨码无在线| 亚洲中文字幕久爱亚洲伊人| 国产亚洲一本二本三道|