鄒春艷

[摘要] 目的 探討對妊娠期糖尿病患者實施血漿D-二聚體+纖維蛋白原檢測的臨床價值。方法 選擇該院2017年4月—2019年6月收治的82例妊娠期糖尿病患者作為研究實驗組;同時間段選擇82名健康孕婦作為研究參照組;針對兩組孕婦均展開血漿D-二聚體+纖維蛋白原檢測操作，就組間檢測結(jié)果展開對比。結(jié)果 實驗組纖維蛋白原水平為（256.29±51.03）mg/dL;血漿D-二聚體水平為（2 312.16±515.25）μg/mL;參照組纖維蛋白原水平為（165.29±51.12）mg/dL;血漿D-二聚體水平為（550.25±152.63）μg/mL;最終發(fā)現(xiàn)，實驗組妊娠期糖尿病患者纖維蛋白原水平以及D-二聚體水平均高于參照組健康孕婦明顯（P<0.05）;實驗組失血量為（600.12±42.16）mL;參照組為（400.23±52.22）mL;最終發(fā)現(xiàn)，實驗組妊娠期糖尿病患者產(chǎn)后失血量高于參照組健康孕婦明顯（P<0.05）。結(jié)論 妊娠期糖尿病患者于臨床接受診斷期間，血漿D-二聚體+纖維蛋白原檢測工作的合理開展，可以對患者體內(nèi)高凝狀態(tài)以及纖溶狀態(tài)進行有效判斷，對于妊娠期糖尿病患者的病情發(fā)展以及疾病預(yù)后評估表現(xiàn)出顯著價值。

[關(guān)鍵詞] 血漿D-二聚體;纖維蛋白原改變;妊娠期糖尿病;檢測結(jié)果

[中圖分類號] R587 ? ? ? ? ?[文獻標(biāo)識碼] A ? ? ? ? ?[文章編號] 1672-4062（2020）06（a）-0020-03

[Abstract] Objective To explore the clinical value of plasma D-dimer+fibrinogen detection in patients with gestational diabetes. Methods 82 patients with gestational diabetes who were admitted to the hospital from April 2017 to June 2019 were selected as the research experimental group; at the same time， 82 healthy pregnant women were selected as the research reference group; plasma D-II polymer + fibrinogen test operation was developed for both groups of pregnant women， comparing the test results between two groups. Results The fibrinogen level of the experimental group was （256.29±51.03）mg/dL; the plasma D-dimer level was （2 312.16±515.25）μg/mL; the fibrinogen level of the reference group was （165.29±51.12）mg/dL; the plasma D-dimer level was（550.25±152.63）μg/mL; it was finally found that the fibrinogen level and D-dimer level of gestational diabetes patients in the experimental group were significantly higher than that of the healthy pregnant women in the reference group（P<0.05）; The blood loss of the experimental group was （600.12±42.16）mL; the reference group was （400.23±52.22）mL; Finally， it was found that the postpartum blood loss of gestational diabetes patients in the experimental group was higher than that of the healthy pregnant women in the reference group（P<0.05）. Conclusion During the clinical diagnosis of gestational diabetes patients， the reasonable development of plasma D-dimer+fibrinogen detection can effectively judge the hypercoagulable state and fibrinolysis state of the patients， and the disease development and disease prognosis assessment show significant value of gestational diabetes patients.

[Key words] Plasma D-dimer; Fibrinogen changes; Gestational diabetes; Test results

妊娠期糖尿病主要是孕婦在妊娠階段呈現(xiàn)出體內(nèi)糖代謝紊亂的現(xiàn)象，屬于發(fā)病率尤為顯著的一種妊娠期并發(fā)癥[1]。妊娠期糖尿病狀態(tài)下的患者，會使得自身以及胎兒受到程度不同影響。在人們生活觀念以及方式逐漸改變情形下，患有妊娠期糖尿病患者例數(shù)增加趨勢較為顯著，對此確定有效方法就此種疾病給予防治意義顯著[2]。人體在呈現(xiàn)出糖代謝紊亂以及脂代謝紊亂的情況后，會對應(yīng)表現(xiàn)出血液流變學(xué)變化以及凝血功能變化的情況。針對人體高凝狀態(tài)以及繼發(fā)性纖溶亢進在進行評價期間，血漿D-二聚體以及纖維蛋白原屬于應(yīng)用率較為顯著的特異性指標(biāo)，通過對此兩種指標(biāo)實時測定，能夠?qū)膊☆A(yù)后進行有效評估，對于臨床治療方案的研究進行充分指導(dǎo)[3]。該次研究將針對2017年4月—2019年6月收治的82例妊娠期糖尿病患者與同時期的82名健康孕婦為研究對象，探究對其實施血漿D-二聚體+纖維蛋白原檢測的可行性，以利于妊娠期糖尿病患者病情發(fā)展以及疾病預(yù)后的有效評估。現(xiàn)報道如下。