李菲 劉龍魂 殷致富
【摘要】 目的:探討濕疹對幼兒生長發(fā)育的影響。方法:將筆者所在醫(yī)院2017年9月-2018年2月收治的50例濕疹幼兒設為觀察組,將同期接受健康檢查的50例健康幼兒設為對照組,觀察組幼兒予以糖皮質激素乳膏+潤膚劑外用治療,飲食回避,對照組幼兒常規(guī)飲食,兩組幼兒隨訪12個月,比較兩組幼兒隨訪3、6、12個月的年齡別體重Z評分(WAZ)、年齡別身高Z評分(LAZ)、認知發(fā)育情況。結果:對照組隨訪3、6、12個月的WAZ、LAZ、發(fā)育商評分均高于觀察組,差異均有統(tǒng)計學意義(P<0.05)。結論:濕疹的發(fā)生對幼兒生長發(fā)育具有一定的阻礙作用。
【關鍵詞】 濕疹; 幼兒; 生長發(fā)育; 體格發(fā)育; 認知發(fā)育
doi:10.14033/j.cnki.cfmr.2019.19.072 文獻標識碼 B 文章編號 1674-6805(2019)19-0-03
Effect of Eczema on the Growth and Development of Young Children/LI Fei,LIU Longhun,YIN Zhifu.//Chinese and Foreign Medical Research,2019,17(19):-160
【Abstract】 Objective:To investigate the effects of eczema on the growth and development of young children.Method:A total of 50 cases of eczema children admitted to our hospital from September 2017 to February 2018 were set as observation group.50 healthy children who received health check during the same period were set as control group.The children in the observation group were treated with Glucocorticoid Cream combined moisturizer and diet avoidance,the control group children were given regular diet,and the two groups of children were followed up for 12 months.The weight-for-age z-score(WAZ),length-for-age z score(LAZ) and cognitive development were compared between the two groups of children at 3,6 and 12 months.Result:The WAZ,LAZ and developmental quotient scores at 3,6 and 12 months were higher in the control group than those in the observation group,the differences were statistically significant(P<0.05).Conclusion:The occurrence of eczema has a certain hindrance to the growth and development of young children.
【Key words】 Eczema; Young children; Growth and development; Physical development; Cognitive development
First-authors address:Tangxia Hospital of Dongguan City,Dongguan 523710,China
濕疹在我國臨床較常見,是指由多種內外因素引起的一種皮膚炎性反應,發(fā)病后臨床癥狀主要表現(xiàn)劇烈的皮膚瘙癢,延誤治療或治療不當會造成較嚴重的皮損[1]。嬰幼兒由于胃腸道發(fā)育不完善,為發(fā)生濕疹的主要群體[2]。長期臨床觀察發(fā)現(xiàn),幼兒發(fā)生濕疹后,除皮損癥狀外,可伴隨出現(xiàn)嘔吐、腹脹、腹瀉等多種胃腸道癥狀,阻礙機體對營養(yǎng)物質的消化和吸收,另外,嚴重的皮膚瘙癢會影響睡眠,繼而可能會增加幼兒發(fā)生營養(yǎng)不良性相關疾病的風險[3]。為進一步明確幼兒濕疹與生長發(fā)育之間的關系,本研究選取50例濕疹幼兒和50例健康幼兒作為研究對象,分析和探討濕疹對幼兒生長發(fā)育的影響,現(xiàn)報告如下。
1 資料與方法
1.1 一般資料
研究對象為筆者所在醫(yī)院2017年9月-2018年2月收治的50例濕疹幼兒設為觀察組,濕疹的診斷以中華醫(yī)學會皮膚性病學分會免疫學組制定的《濕疹診療指南》(2011年版)為參考,除外早產兒、小于胎齡兒、出生低體重兒、唇腭裂及嚴重出生缺陷兒如心、肝、腎疾病等。同期來筆者所在醫(yī)院接受健康檢查的50例健康幼兒設為對照組。觀察組,男28例,女22例;年齡1~3歲,平均(1.40±0.50)歲。對照組,男24例,女26例;年齡1~2.5歲,平均(1.35±0.30)歲。兩組幼兒的性別、年齡等一般資料比較,差異無統(tǒng)計學意義(P>0.05),有可比性。本研究在獲取幼兒家屬知情、同意后實施。
1.2 方法
觀察組幼兒予以糖皮質激素乳膏(芙美松,浙江仙琚制藥股份有限公司生產,國藥準字H20050610)+潤膚劑外用治療,采取高蛋白飲食回避如牛奶、雞蛋、蝦、蟹、海魚.對照組幼兒常規(guī)飲食,不回避高蛋白食物。比較兩組幼兒隨訪3、6、12個月的體格發(fā)育情況、認知發(fā)育情況。