朱丹 李學(xué)臣

[摘要] 目的 探討兒童營(yíng)養(yǎng)性維生素D缺乏性佝僂病合并缺鐵性貧血的臨床治療。 方法 納入我院2017年8月～2018年9月收治的88例兒童營(yíng)養(yǎng)性維生素D缺乏性佝僂病合并缺鐵性貧血患兒。按隨機(jī)數(shù)字表分組，常規(guī)治療組采取常規(guī)補(bǔ)充維生素D和補(bǔ)鐵治療，綜合治療組則采取綜合治療。比較常規(guī)治療組、綜合治療組臨床效果、缺鐵性貧血糾正的時(shí)間、住院時(shí)間;治療前后患兒營(yíng)養(yǎng)指標(biāo)、血紅蛋白水平;副反應(yīng)。 結(jié)果 綜合治療組總有效率為93.18%，常規(guī)治療組為68.18%，差異有統(tǒng)計(jì)學(xué)意義（χ2=8.212，P<0.05）。綜合治療組副反應(yīng)與常規(guī)治療組比較，無(wú)明顯差異（χ2=0.000，P>0.05）;綜合治療組缺鐵性貧血糾正的時(shí)間、住院時(shí)間分別為（8.11±1.21）d、（13.13±0.78）d，常規(guī)治療組分別為（12.44±2.21）d、（18.23±1.54）d，綜合治療組明顯優(yōu)于常規(guī)治療組，差異有統(tǒng)計(jì)學(xué)意義（t=6.801、6.012，P<0.05）。治療后綜合治療組營(yíng)養(yǎng)指標(biāo)ALB、TP、血紅蛋白水平分別為（35.01±5.23）g/L、（64.58±8.11）g/L、（92.19±2.22）mg/L，顯著優(yōu)于常規(guī)治療組的（32.34±4.21）g/L、（61.11±7.12）g/L、（79.23±2.25）mg/L，差異有統(tǒng)計(jì)學(xué)意義（t=9.073、10.733、15.872，P<0.05）。 結(jié)論 綜合治療兒童營(yíng)養(yǎng)性維生素D缺乏性佝僂病合并缺鐵性貧血效果理想，可有效糾正貧血，改善血紅蛋白和營(yíng)養(yǎng)指標(biāo)。

[關(guān)鍵詞] 兒童;營(yíng)養(yǎng)性維生素D缺乏;佝僂病;缺鐵性貧血

[中圖分類號(hào)] R723.2;R725.5? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1673-9701（2019）09-0035-04

[Abstract] Objective To explore the clinical treatment of children with nutritional vitamin D deficiency rickets combined with iron deficiency anemia. Methods A total of 88 children with nutritional vitamin D deficiency rickets and iron deficiency anemia in our hospital from August 2017 to September 2018 were included. Patients were randomized into two groups according to random numbers. The conventional treatment group was given conventional vitamin D supplementation and iron supplementation， while the comprehensive treatment group was given comprehensive treatment. The therapeutic effects of the two groups， the time of correction of iron deficiency anemia， and the length of hospital stay were compared. The nutritional indicators and hemoglobin levels of the children before and after treatment were compared. The incidence of side effects was compared between the two groups. Results The effective rate of treatment in the comprehensive treatment group was 93.18%， which was significantly higher than that in the conventional treatment group （68.18%）， the difference was statistically significant （χ2=8.212， P<0.05）. There was no significant difference in the incidence of side effects between the two treatment groups（χ2=0.000， P>0.05）. The correction time of iron deficiency anemia and hospitalization time in the comprehensive treatment group were （8.11±1.21）d and （13.13±0.78）d， respectively， which were significantly shorter than those of the conventional treatment group[（12.44±2.21）d， and （18.23±1.54）d]， the difference was statistically significant（t=6.801， 6.012， P<0.05）. After treatment， the nutritional indicators of ALB， TP and hemoglobin were （35.01±5.23） g/L， （64.58±8.11） g/L， and （92.19±2.22） mg/L in the comprehensive treatment group， which were higher than those of the conventional treatment group[（32.34±4.21） g/L， （61.11±7.12） g/L， and （79.23±2.25） mg/L]， the difference was statistically significant（t=9.073， 10.733， and 15.872， respectively， P<0.05）. Conclusion Comprehensive treatment is effective in children with nutritional vitamin D deficiency rickets combined with iron deficiency anemia， which can effectively correct anemia， and improve hemoglobin and nutritional indicators.