王照軍 陸西平
[摘要] 目的 在搶救產(chǎn)科急性彌漫性血管內(nèi)凝血患者中應(yīng)用成分輸血與全血輸注,以此分析成分輸血與全血輸注對患者臨床效果的影響。方法 方便選擇產(chǎn)科急性彌漫性血管內(nèi)凝血患者,共計100例,選擇時間于2014年3月—2015年3月期間,行不同的輸血方式:成分輸血、全血輸注,對應(yīng)組別:研究組、對照組。經(jīng)系統(tǒng)軟件分析組間的輸血后不良反應(yīng)發(fā)生率、PLT、RBC、HGB、HCT、凝血酶原時間(PT)、凝血酶原時間(APTT)、FGB、凝血酶時間(TT)、D-D數(shù)據(jù)指標(biāo)。 結(jié)果 研究組的輸血后不良反應(yīng)發(fā)生率(4.00%)、凝血酶原時間(APTT)(25.66±3.22)s經(jīng)系統(tǒng)軟件分析發(fā)現(xiàn)低于對照組,且研究組的PLT(98.22±8.76)×109/L、FGB(1.67±0.16)g/L高于對照組,差異有統(tǒng)計學(xué)意義(χ2=5.01,t=6.07,6.22, 7.21,P<0.05);研究組與對照組之間的RBC、HGB、HCT、凝血酶原時間(PT)、凝血酶時間(TT)、D-D數(shù)據(jù)指標(biāo)差異無統(tǒng)計學(xué)意義(P>0.05)。 結(jié)論 成分輸血在搶救產(chǎn)科急性彌漫性血管內(nèi)凝血患者中更為安全有效,但是,還需要依據(jù)患者的具體血液學(xué)指標(biāo)進(jìn)行成分輸血方案制定,以此確保搶救效果。
[關(guān)鍵詞] 成分輸血;全血輸注;產(chǎn)科;急性彌漫性血管內(nèi)凝血;搶救;臨床效果
[中圖分類號] R457.1 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-0742(2019)03(b)-0039-03
[Abstract] Objective To analyze the effects of transfusion and whole blood transfusion on the clinical outcomes of patients with acute diffuse intravascular coagulation in obstetrics. Methods A total of 100 patients with acute diffuse intravascular coagulation in obstetrics were convenient selected. The selection time was from March 2014 to March 2015. Different blood transfusion methods were used: component transfusion, whole blood transfusion, corresponding group: study group, control group. The incidence of adverse reactions after transfusion, PLT, RBC, HGB, HCT, prothrombin time (PT), prothrombin time (APTT), FGB, thrombin time (TT), D-D data index were analyzed by system software. Results The incidence of adverse reactions after transfusion (4.00%) and prothrombin time (APTT) (25.66±3.22)s in the study group were lower than those in the control group, and the PLT of the study group (98.22±8.76)×109/L, FGB (1.67±0.16) g/L higher than the control group,the difference was statistically significant(χ2=5.01,t=6.07,6.22,7.21,P<0.05); there was no difference in RBC, HGB, HCT, prothrombin time (PT), thrombin time (TT), D-D data between the study group and the control group, P>0.05. Conclusion Component transfusion is safer and more effective in the rescue of patients with acute disseminated intravascular coagulation in obstetrics. However, it is also necessary to formulate a component transfusion protocol based on the specific hematological parameters of the patient to ensure the rescue effect.
[Key words] Component transfusion; Whole blood transfusion; Obstetrics; Acute diffuse intravascular coagulation; Rescue; Clinical effect
產(chǎn)科急性彌漫性血管內(nèi)凝血具有極高的病死率,該病癥發(fā)病極為迅速,主要的病癥特點(diǎn)是大出血,也是目前臨床上造成孕產(chǎn)婦死亡的主要原因。失血性休克或過敏性休克一般是引發(fā)產(chǎn)科急性彌漫性血管內(nèi)凝血患者的常見疾病原因,且該種病癥會早于產(chǎn)科急性彌漫性血管內(nèi)凝血的診斷時間,新鮮全血成為了以往血液制品的主要供應(yīng)方式。隨著近年來臨床輸血研究不斷發(fā)展和進(jìn)步,成分血制品的應(yīng)用價值受到關(guān)注和重視;在產(chǎn)科急性彌漫性血管內(nèi)凝血患者的搶救中,成分輸血占據(jù)重大臨床作用。該文在搶救產(chǎn)科急性彌漫性血管內(nèi)凝血患者中應(yīng)用成分輸血與全血輸注(患者選擇時間于2014年3月—2015年3月期間,共計100例),以此分析成分輸血與全血輸注對患者臨床效果的影響。