劉瑩

[摘要] 目的 探討在小兒重癥肺炎患兒中氨溴索+人免疫球蛋白與小劑量多巴胺+多巴酚丁胺治療的效果。 方法 此次方便抽選2017年2月—2019年2月期間該院醫(yī)治的64例小兒重癥肺炎患兒做研究，隨機分為對照組（32例）、研究組（32例）?；純壕Ｒ?guī)治療，對照組患兒加小劑量多巴胺+多巴酚丁胺治療，而研究組患兒加氨溴索+人免疫球蛋白治療，對比兩組的治療費用、治療時間、體征改善時間、治療效果。 結果 研究組的治療費用（1 520.12±135.84）元高于對照組（1 161.21±110.25）元，差異有統(tǒng)計學意義（t=11.604，P=0.000）。研究組的治療時間（6.61±1.12）d、肺部啰音消失時間（3.20±0.76）d、三凹征消失時間（2.61±0.91）d、心率改善時間（3.40±0.15）d、呼吸改善時間（2.20±0.17）d均短于對照組患兒[（8.13±1.84）d、（4.41±0.73）d、（3.54±1.02）d、（4.50±0.18）d、（3.25±0.14）d]，差異有統(tǒng)計學意義（t=3.992、6.495、3.849、26.557、26.971，P=0.000）。研究組的治療總有效率（93.75%）高于對照組（90.63%），但差異無統(tǒng)計學意義（χ2=0.217，P=0.641）。 結論 在小兒重癥肺炎患兒中，氨溴索+人免疫球蛋白與小劑量多巴胺+多巴酚丁胺治療的總有效率相近，其中，氨溴索+人免疫球蛋白的治療費用高，但是該方法的治療時間短、患兒體征改善時間短。

[關鍵詞] 小兒重癥肺炎;氨溴索;人免疫球蛋白;多巴胺;多巴酚丁胺;療效

[中圖分類號] R5 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1674-0742（2019）06（c）-0115-03

[Abstract] Objective To investigate the effect of ambroxol + human immunoglobulin and low-dose dopamine + dobutamine in children with severe pneumonia. Methods Conveniently selected sixty-four children with severe pneumonia in our hospital who were treated in our hospital from February 2017 to February 2019 were randomly divided into the control group （32 cases） and the study group （32 cases）. All children were treated routinely. The control group received low-dose dopamine + dobutamine treatment， while the study group received ambroxol + human immunoglobulin treatment. The treatment cost， treatment time and physical signs recovery time， treatment effect of the two groups were improved. Results The treatment cost of the study group （1 520.12±135.84）yuan was higher than that of the control group （1 161.21±110.25） yuan， and the difference was significant（t=11.604， P=0.000）. The treatment time of the study group （6.61±1.12） d， the disappearance time of the lungs （3.20±0.76） d， the disappearance time of the three concave signs （2.61±0.91） d， the heart rate improvement time （3.40±0.15） d， the respiratory improvement time （2.20±0.17） d were shorter than those in the control group [（8.13±1.84） d， （4.41±0.73） d， （3.54±1.02） d， （4.50±0.18） d， （3.25±0.14） d]， the difference was statistically significant （t=3.992， 6.495， 3.849， 26.557， 26.971， P=0.000）. The total effective rate of treatment in the study group （93.75%） was higher than that in the control group （90.63%）， but the difference was not statistically significant （χ2=0.217， P=0.641）. Conclusion In children with severe pneumonia， the total effective rate of ambroxol + human immunoglobulin and low-dose dopamine + dobutamine is similar. Among them， ambroxol + human immunoglobulin is expensive. However， the method has a short treatment time and a short improvement in the physical signs of the child.