亚洲免费av电影一区二区三区,日韩爱爱视频,51精品视频一区二区三区,91视频爱爱,日韩欧美在线播放视频,中文字幕少妇AV,亚洲电影中文字幕,久久久久亚洲av成人网址,久久综合视频网站,国产在线不卡免费播放

        ?

        Influence of different portal vein branches on hepatic encephalopathy during intrahepatic portal shunt via jugular vein

        2022-12-02 15:41:08XinYaoShengHeMengWeiJianPingQin
        World Journal of Gastroenterology 2022年31期

        Xin Yao, Sheng He,Meng Wei,Jian-Ping Qin

        Abstract This letter is regarding the study titled ‘Targeted puncture of left branch of intrahepatic portal vein in transjugular intrahepatic portosystemic shunt (TIPS) to reduce hepatic encephalopathy’. Prior to the approval of TIPS dedicated stents(Viatorr stents) in China in October 2015, Fluency covered stents were typically used. As Fluency covered stents have a strong support force and axial elastic tension, a ‘cap’ may form if the stent is located too low at the end of the hepatic vein or too short at the end of the portal vein during surgery, leading to stent dysfunction. Since the blood shunted by the stent is from the main trunk of the portal vein, the correlation between the incidence of postoperative hepatic encephalopathy and the location of the puncture target (left or right portal vein branch) is worth discussion. Notably, no studies in China or foreign countries have proven the occurrence of left and right blood stratification after the accumulation of splenic vein and mesenteric blood flow in the main trunk of the portal vein in patients with cirrhotic portal hypertension.

        Key Words: Viatorr stent; Portosystemic shunt; Transjugular intrahepatic; Hypertension;portal; Left and right portal vein branches

        TO THE EDlTOR

        We read the article of Luoet al[1] titled “Targeted puncture of left branch of intrahepatic portal vein in transjugular intrahepatic portosystemic shunt (TIPS) to reduce hepatic encephalopathy” and are very interested in its conclusions. We think that therapy by “targeted puncture of the left branch of the intrahepatic portal vein in TIPS to reduce hepatic encephalopathy” is worthy of discussion.

        First, Luoet al[1] performed a retrospective analysis of portal hypertension patients receiving TIPS from January 2000 to January 2013. During this period, a shunt was established using a Fluency stent(BARD, Voisins le Bretonneux, France) or Viatorr stent (W.L. Gore & Associates, Flagstaff, AZ, United States). However, the shunts were established in TIPS mainly using Fluency covered stents in China before the approval of TIPS dedicated stents (Viatorr stents) in China in October 2015. As Fluency covered stents have a strong support force and axial elastic tension, a ‘cap’ may form if the stent is located too low at the end of the hepatic vein or too short at the end of the portal vein during the operation, thereby leading to stent dysfunction. Since the blood shunted by the stent is from the main trunk of the portal vein, as shown in Figure 2 of Luoet al’s paper (the stent is inserted into the main trunk of the portal vein at the end of the portal vein for shunts in both the left and right portal vein branches), the correlation between the incidence of postoperative hepatic encephalopathy and the location of the puncture target (left or right portal vein branch) is worthy of discussion.

        As pointed out by Luoet al[1], prior studies have reported that the backflow blood from the splenic and superior mesenteric veins is not thoroughly mixed but rather enters the left and right portal vein branches separately,i.e., the blood from the superior mesenteric vein mainly flows into the right branch,while the blood from the splenic vein mainly flows into the left branch[2-3]. In a study on corrosion casting of the portal vein and hepatic artery ramifications in dogs, this study focused on explaining the anatomical features of the hepatic portal vein and hepatic artery in animals instead of the blood flow features of the portal vein system[2]. The author team believes that a substantial difference between animals and humans. In a study using carbon dioxide angiography, iodinated contrast medium was used to replace traditional angiography[3]. This study included chronic liver disease patients receiving percutaneous transhepatic puncture of the portal vein with the tube inserted into the splenic vein; a mechanical injection system was used to inject a total volume of 30 mL of contrast medium at a speed of 5 mL/s. Notably, a difference was observed in blood mixing at the left and right sides of the main trunk of the portal vein. An early study conducted in United States of America found that an increase in the pressure in the portal vein was followed by a decrease in hepatic blood inflow and blood flow rate and grading of liver function due to hepatic sinusoidal obstruction, perisinusoidal fibrosis and portal vein obstruction in cirrhosis was related to the portal blood flow rate; furthermore, portal hypertensive liver function damage was obvious, and the portal blood flow rate was low[4]. In the hyperdynamic splanchnic circulatory state, the progressive decrease in the portal blood flow rate suggests aggravation of hepatic parenchymal lesions and increased portal blood flow resistance. The author team believes that the blood flow rate decreased after splenic vein and mesenteric blood flows accumulated in the main trunk of the portal vein in cirrhotic portal hypertension patients, and so it was necessary to define the presence of different blood flow rates after the blood flows accumulated in the main trunk of the portal vein so as to achieve left and right blood stratification in the natural state. However, it is controversial at home and abroad whether there is difference between splenic vein blood flow velocity and mesenteric blood flow velocity in cirrhotic patients with portal hypertension after the accumulation of the main portal vein in the natural state. In a study conducted in 2020 in China, 15 patients with liver cirrhosis and upper gastrointestinal haemorrhage received TIPS, and blood samples were collected from the left branch, right branch and main trunk of the portal vein during the operation[5]. In these patients,the plasma ammonia concentration (μmol/L) was 96.4 ± 17.6 for the left branchvs113.5 ± 18.4 for the right branchvs106.9 ± 38.7 for the main trunk, without any statistically significant differences (P> 0.05).This study provides important evidence for the comparison of blood bacterial metabolites in the left and right branches of the cirrhotic portal vein.

        TIPS dedicated stents (Viatorr stents) have been adopted for surgery at the Center since March 2016.In previous studies, COOK bare stents with an inner diameter of 8 mm were used to establish a shunt[6-7]. Although such a stent should be long enough at the end of the portal vein, the shunted blood was from the portal vein branches, so whether a shunt was established in the left or right portal vein branch had no significant effect on the incidence of hepatic encephalopathy. In a study conducted in China in 2020, 120 cirrhotic portal hypertension patients received TIPS using Viatorr stents. Intraoperative portal vein angiography showed that a shunt was established in the left portal vein branch for 52 patients and in the right portal vein branch for 68 patients[8]. There was no statistically significant difference in the incidence of postoperative hepatic encephalopathy (χ2= 0.159,P= 0.69) between the left portal vein and right portal vein branch shunting groups. A recent study reported that the incidence of hepatic encephalopathy decreased significantly by controlling the inner diameter of the stent,i.e., using a Viatorr stent with an inner diameter of 8 mm[9]. The bare area of a Viatorr stent may guarantee a smooth blood flow in the portal vein and prevent more blood not metabolised by the liver from directly entering the systemic circulation.

        There is no information in the TIPS guidelines circulated in North America regarding differences in the incidence of postoperative hepatic encephalopathy when shunts are established in different portal vein branches[10-11]. We believe that there are no differences in the incidence of hepatic encephalopathy among postoperative patients when using a Viatorr stent with an inner diameter of 8 mm when the shunt is established in the left or right portal vein branch. As the postoperative medium and long-term efficacy of TIPS are related to clinical procedures, postoperative management of patients and other factors, future studies with larger sample sizes and multicentre randomised controlled trials are warranted.

        FOOTNOTES

        Author contributions:All authors wrote and edited the manuscript.

        Conflict-of-interest statement:The authors declare no competing interests for this manuscript.

        Open-Access:This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

        Country/Territory of origin:China

        ORClD number:Xin Yao 0000-0002-9977-6153; Sheng He 0000-0002-4468-0728; Meng Wei 0000-0001-6197-9812; Jian-Ping Qin 0000-0001-7834-8830.

        S-Editor:Chang KL

        L-Editor:A

        P-Editor:Chang KL

        亚洲最大av在线精品国产| 亚洲中文无码成人影院在线播放| 精品国产免费Av无码久久久| 亚洲国产日韩综一区二区在性色| 蜜桃视频羞羞在线观看| 男女猛烈无遮挡免费视频| 中国一 片免费观看| 国产av一区二区三区丝袜| 午夜一区二区三区免费观看| 色综合久久网| 午夜福利麻豆国产精品| 亚洲av不卡电影在线网址最新| 中文字幕一区二区网址| 丰满人妻熟妇乱又仑精品| 色哟哟网站在线观看| 成年奭片免费观看视频天天看| 国产在线视频一区二区三区| 成熟了的熟妇毛茸茸| 久久久久久免费毛片精品| 日本口爆吞精在线视频| 草青青视频手机免费观看| 中文字幕有码无码人妻av蜜桃 | 初尝黑人巨砲波多野结衣| 亚州五十路伊人网| 在线成人影院国产av| 国产精品成人va在线观看| 亚洲AV无码一区二区三区人| 国产毛片三区二区一区| 亚洲成人中文字幕在线视频| 久久综合国产乱子伦精品免费| 伊人久久亚洲综合影院首页| 国产精品视频白浆免费看| 欧美噜噜久久久xxx| a国产一区二区免费入口| 国产免费午夜福利蜜芽无码| 国产自产二区三区精品| 在线欧美中文字幕农村电影| 妺妺窝人体色www在线直播| 亚洲成人av在线播放不卡| 国内精品久久久久国产盗摄 | 亚洲熟女少妇精品久久|