Qiu-Ming Wang, Jian-Ling Du, Zhi-Jun Duan, Shi-Bin Guo, Xiao-Yu Sun, Zhen Liu

Abstract We found a mistake in Figure 6. Panels A (Sham group) and F (DFX group) (180 degrees rotated) is same images. We have replaced the incorrect images (Panels F)with the correct Figure. This error does not change the meaning of the picture or the conclusion of the manuscript. We apologize for our unintentional mistakes,which caused great inconvenience.

Key Words: Heme oxygenase-1; Hepcidin; Iron accumulation; Oxidative stress; Portal vein pressure; Carboxyhemoglobin; Bile duct ligation

TO THE EDlTOR

We found a mistake in Figure 6. Panels A (Sham group) and F (DFX group) (180 degrees rotated) is same images. We have replaced the incorrect images (Panels F) with the correct Figure 1. We only revised the incorrect figure, and the Manuscript NO: 75978 don't need to revise[1].

Figure 1 erl’s Prussian blue staining, levels of hepcidin, serum and liver iron. A: No iron accumulated in the Sham group; B: A small amount of iron mainly accumulated on Kupffer cells in the bile duct ligation (BDL) group; C: Much more iron accumulation was found in interlobular and macrophagocytes in the cobalt protoporphyrin (CoPP) group; D and F: Almost no iron accumulation was detected in the zinc protoporphyrin (ZnPP) group and deferoxamine (DFX) group; E:Massive iron accumulation was observed in the Fe group; G and H: There were no differences in the hepatic and serum iron content of these six groups; I: Plasma hepcidin also was measured by enzyme-linked immuno sorbent assay (magnification × 400). Values are expressed as mean ± SE (n = 6). bP ＜ 0.01 vs Sham group; c P ＜ 0.05, dP ＜ 0.01 vs BDL group; eP ＜ 0.05 vs ZnPP group.

FOOTNOTES

Author contributions:Wang QM and Du JL performed the experiments, analyzed the data and wrote the manuscript;Duan ZJ and Wang QM designed the experiments; Wang QM performed the experiments, analyzed the data and wrote the manuscript; Duan ZJ and Guo SB revised the manuscript.

Conflict-of-interest statement:We declare that we have no conflict of interest.

Open-Access:This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Country/Territory of origin:China

ORClD number:Qiu-Ming Wang 0000-0003-1262-6361; Jian-Ling Du 0000-0003-4782-1052; Zhi-Jun Duan 0000-0001-7976-4959; Shi-Bin Guo 0000-0003-2971-3859; Xiao-Yu Sun 0000-0002-4138-6005; Zhen Liu 0000-0002-9899-8184.

S-Editor:Liu JH

L-Editor:A

P-Editor:Liu JH