亚洲免费av电影一区二区三区,日韩爱爱视频,51精品视频一区二区三区,91视频爱爱,日韩欧美在线播放视频,中文字幕少妇AV,亚洲电影中文字幕,久久久久亚洲av成人网址,久久综合视频网站,国产在线不卡免费播放

        ?

        The role of Si-Jun-Zi decoction in the management of gastric precancerous lesions and its mechanism

        2018-11-13 02:06:46
        Traditional Medicine Research 2018年6期

        Gastric cancer remains one of the most common and aggressive malignant tumors worldwide. The occurence of gastric cancer experiences a cascade of multistep gastric carcinogenesis, starting from inflammation,metaplasia, and ultimately to dysplasia and carcinoma.Patients with gastric precancerous lesions, mainly including intestinal metaplasia and dysplasia, are more prone to suffer from gastric adenocarcinoma [1].Therefore, early prevention and treatment regarding gastric precancerous lesions is an important way to reduce the risk of occurence of gastric cancer.

        At present, the therapy of gastric precancerous lesions main contains H. pylori eradication, the application of cyclooxgenase-2 (COX-2) inhibitor or antioxidants,and/or endoscopic mucosal resection. However, their clinical outcome is limited because they does not appear to reverse intestinal metaplasia but may only slow down the progression to neoplasia [2, 3]. In most cases, “wait and see” strategy, that is, survailing or monitoring the progression of precancerous conditions and lesions,remains the most important guidline in the management of gastric precancerous lesions.

        Si-Jun-Zi (SJZ) decoction, a famous herbal formula originated from Chinese medicine ancient book Taiping Huimin Heji Jufang in 1078 A.D. - 1085 A.D., Song Dynasty of China, has been used to treat digestive diseases for hundreds of years. Clinical studies showed that SJZ decoction could reverse gastric precancerous lesions and had the potential to prevent gastic cancer[4-6]. Due to its multi-compound and multi-target manner,SJZ decoction shows great potential in the prevention of this complex disease. However, at present, the active components and the mechanism of its favorably therapeutic effects, especially the mechanisam from

        In recent years network pharmacology has become a popular methodology for the reasearch of Chinese herbal formular. The network pharmacology approach could provide a novel approach for thoroughly exploring the active components and molecular mechanisms underlying the therapeutic effects of Chinese herbal formular with the aid of Big Database, including the active compounds screening, compound targets of herbal formular, disease targets of GPL, GO and KEGG pathway enrichment and network construction.

        To read more about Si-Jun-Zi decoction, see this artical please: A network pharmacology approach to investigate the mechanisms of Si-Jun-Zi decoction in the treatment of gastric precancerous lesions. Link:https://www.tmrjournals.com/tmr/EN/10.12032/TMR201 814087

        Xiong-Zhi Wu

        Editor-in-Chief of TMR

        1. de Vries AC, van Grieken NC, Looman CW, et al.Gastric cancer risk in patients with premalignant gastric lesions: a nationwide cohort study in the Netherlands. Gastroenterology 2008, 134: 945-952.

        2. Dinis-Ribeiro M, Areia M, de Vries AC, et al.Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy(ESGE), European Helicobacter Study Group(EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva(SPED). Endoscopy 2012, 44: 74-94.

        3. Huh CW, Kim BW. Endoscopic treatment of gastric adenoma. Korean J Gastroenterol 2017, 70: 115-120.

        4. Song FL, Lin YF, Li HR. Effect of Jiawei Sijunzi decoction based triple therapy on atrophic gastritis and expression of PCNA. China J Trad Chin Med Pharm 2009, 4: 367-369.

        5. Ss ZN, Wang ZF, Luo XM. Meta-analysis of modified Sijunzi Tang for treating chronic atrophic gastritis. Chin J Exp Tradi Med Formulae 2015, 21:204-208.

        6. Tang RY, Lin J. Status of clinical studies on treating precancerous lesions of gastric cancer with Chinese herbs. Trad Chin Med 2014, 3: 79-84.

        无码专区人妻系列日韩精品| 日本韩国三级aⅴ在线观看 | 精品国产中文久久久免费| 无码av天天av天天爽| 欧美交换配乱吟粗大25p| 国产爆乳无码一区二区在线 | 狠狠摸狠狠澡| 把插八插露脸对白内射| 日本专区一区二区三区| 久久国产精品亚洲我射av大全| av无码小缝喷白浆在线观看 | 久久久久夜夜夜精品国产| 亚洲成人小说| 日韩av无码午夜福利电影| 亚洲国产精品悠悠久久琪琪| 国产精品免费av片在线观看| 亚洲精品国产成人AV| 元码人妻精品一区二区三区9| h视频在线播放观看视频| 亚洲欧美国产国产综合一区| 精品国产高清一区二区广区 | 狠狠久久精品中文字幕无码| 男女视频网站免费精品播放| 亚洲成av人片一区二区密柚| 风间由美性色一区二区三区| 国产视频网站一区二区三区| 国产自拍av在线观看| 国产国产人免费人成免费视频| 国产丰满老熟女重口对白| 亚洲综合精品在线观看中文字幕 | 六月婷婷久香在线视频| 国产福利小视频在线观看| 亚洲免费一区二区av| 亚洲av无码一区二区三区网址| 国产精品无码日韩欧| 日本韩国黄色三级三级| 国产毛女同一区二区三区| 色欲人妻综合网| 久久精品成人亚洲另类欧美| 亚洲中文字幕日韩综合| 漂亮人妻被中出中文字幕久久 |