EDITORIALS

95 Growing Up: Evolving Concepts of Adult Attention De fi cit Hyperactivity Disorder

Philip Shaw

97 Antisuicidal Effects of Ketamine: A Promising First Step

Madhukar H. Trivedi

99 Why Apathy in Alzheimer’s Matters

David L. Sultzer

101 Optimizing the Pharmacologic Treatment of Individuals With First-Episode Psychosis Donald C. Goff

TREATMENT IN PSYCHIATRY

103 Prolonged Postconcussive Symptoms

Davin K. Quinn, et al.

PERSPECTIVES IN GLOBAL MENTAL HEALTH

112 The “Loss of Pride” Syndrome in Yazidi Refugees

Rami Bou Khalil, et al.

REVIEWS AND OVERVIEWS

114 The Neurodevelopmental Basis of Early Childhood Disruptive Behavior: Irritable and

Callous Phenotypes as Exemplars Lauren S. Wakschlag, et al.

ARTICLES

131 Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial

Dorothy K. Sit, et al.

140 Late-Onset ADHD Reconsidered With Comprehensive Repeated Assessments Between Ages 10 and 25

Margaret H. Sibley, et al.

150 The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

Samuel T. Wilkinson, et al

159 Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer’s Disease: A Double-Blind,Randomized, Placebo-Controlled Trial

Prasad R. Padala, et al.

169 Psychopharmacological Treatment in the RAISE-ETP Study: Outcomes of a Manual and Computer Decision Support System Based Intervention

Delbert G. Robinson, et al.

180 Cortical Functional Connectivity Evident After Birth and Behavioral Inhibition at Age 2

Chad M. Sylvester, et al.

LETTERS TO THE EDITOR

188 The Impact of Underpowered Studies on Clinical Trial Results

Arif Khan, et al.

188 The Importance of Adequately Powered Clinical Studies: Response to Khan et al.

Stephen R. Marder, et al.

189 Pharmacogenetic Tests in Psychiatry

Chad Bousman, et al.

BOOK FORUM

190 The Psychoses of Menstruation and Childbearing

191 Public Health Perspectives on Depressive Disorders