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Call for Papers Special Issue on“Biomarkers for Human Diseases and Translational Medicine’’

The journal Genomics，Proteomics & Bioinformatics（GPB）is now inviting submissions for a special issue（to be published in the fall of 2016）on the topic of“Biomarkers for Human Diseases and Translational Medicine’’.

In the personalized medicine era，disease biomarkers have potential application in diagnosis，prognosis，and guidance for treatment，and are important tools in translational medicine. Diagnosis upon biomarkers would aid in early and more efficient intervention，while prognostic biomarkers could lead to right decision of medical treatment. In addition，the biomarker responses to drug treatment are critical for stratifying patient population to fulfill precision medicine. Traditionally，detection to biomarkers is focused on DNA，RNA，protein or metabolites；moreover，recent advances in biology and medicine have suggested that new molecular types are emerging as biomarkers such as noncoding RNAs，epigenetic modifications，splice isoforms，abnormal proteins and autoantibodies. Furthermore，large-scale and high-throughput analysis technologies，such as genome sequencing and mass spectrometry，greatly promote the discovery and application of biomarkers in human diseases. These technologies provide an excellent opportunity to（1）develop new algorithms deal with the large datasets，（2）identify biomarkers of new data types as aforementioned，and（3）improve the accuracy and robustness in discovery and verification of biomarkers.

To highlight the recent cutting-edge studies and progress in this area，we are pleased to announce a special issue on“Biomarkers for Human Diseases and Translational Medicine’’in GPB，which will publish a set of research articles and review papers focusing on biomarker discovery and applications for human diseases. Dr. Siqi Liu from Beijing Institute of Genomics，Chinese Academy of Sciences and Dr. Edwin Wang from the National Research Council Canada are Guest Editors of this issue.

The topics may include（but not be limited to）:

?Discovery of disease biomarkers using next-generation sequencing

?Biomarkers of new data types such as miRNA，lncRNA，epigenetic modifications，splice isoforms，etc

?Discovery of disease biomarkers through evaluation of gene expression

?Exploration and application of disease protein biomarkers using proteomic analysis

?Alternation of metabolic pathways responding to disease

?Integration of omics data for discovery of disease biomarkers

?High-throughput platforms for biomarker discovery

?Techniques for measurement of disease biomarkers in the clinical diagnosis

?Algorithm development for biomarker discovery

Original studies，reviews，methods，application notes，etc. are all welcome. The portfolio will be open for incoming manuscripts till April 30，2016. Accepted submissions will be published free of charge.

Manuscripts should be submitted online at http://ees.elsevier.com/gpb/. Please indicate that the submission is for this special issue. The detailed Guide for Authors is available on this website as well，with manuscript template and EndNote Output style template provided.

For further information，please contact us:

Dr. Liu（siqiliu@big.ac.cn）；

Dr. Wang（Edwin.Wang@cnrc-nrc.gc.ca）；

Editorial Office（editor@big.ac.cn）.