亚洲免费av电影一区二区三区,日韩爱爱视频,51精品视频一区二区三区,91视频爱爱,日韩欧美在线播放视频,中文字幕少妇AV,亚洲电影中文字幕,久久久久亚洲av成人网址,久久综合视频网站,国产在线不卡免费播放

        ?

        211272 Protective effects of sodium ferulate in vascular endothelial function during cardiopulmonary bypass

        2011-08-15 00:54:32LiaoJianyi廖健毅SoochowUnivAffilChildenHospSuzhou215003ChinThoracCardiovascSurg201127221223
        外科研究與新技術(shù) 2011年3期

        /Liao Jianyi(廖健毅,Soochow Univ Affil Childen’s Hosp,Suzhou 215003)…∥Chin J Thorac Cardiovasc Surg.-2011,27(4).-221~223

        ObjectiveCardiopulmonary bypass(CPB)and its related ischemia reperfusion injury may cause endothelial cell injury.To study the protective effects of sodium ferulate in vascular endothelial function during CPB by testing the changes of vascular endothelial cell(CEC),nitric oxide(NO)and endothelin-1(ET-1)in children with congenital heart disease.MethodsSixty patients with congenital heart disease,including 28 males and 32 females were studied.The mean age was(19.7 ± 10.4)months and body weight(10.5 ±6.1)kg.There were 37 VSD,8 ASD,7 TOF,5 TAPVC and 3 CAVC,among them 26 patients had pulmonary hypertension.They were randomly divided into two groups:sodium ferulate group(group S,n=30),and control group(group C,n=30).Sodium ferulate(8 mg/kg)was given intravenously before CPB.Blood samples were taken from the arterial line at following time points:before CPB(TO),bypass 30 min(Tl),the termination of CPB(T2),2h after operation(T3)and 6h after operation(T4),respectively for determination the concentration of vascular endothelial cell(CEC)in the blood,the concentration of nitric oxide(NO)and endothelin-1(ET-1)in the plasma.ResultsThere were no significant difference for the two groups regarding above parameters at TO(P >0.05).The level of CEC was significantly elevated after CPB in both groups(P <0.05).CEC were lower at T2in group S than in group C(P <0.05).NO was decreased in both groups,but was higher in group S at T2,T3 and T4(P <0.05).The concentration of plasma ET-1 was not significantly different before CPB,but there was a slight decrease at T1,and then it was significantly increased in both groups(P <0.05).But it was lower in group S than in group C at T1,T2,T3 and T4(P <0.05 orP < 0.01).ConclusionThere was severe endothelial cell damage during CPB.Sodium Ferulate can effectively antagonize the secretion of ET-1 to promote the formation of NO.Therefore,it reduces CPB-induced endothelial cell damage and protects vascular endothelial function during CPB.20 refs,1 tab.

        久久久久亚洲av无码专区首 | 无码AV无码免费一区二区| 久久久精品久久久国产| 熟妇高潮一区二区三区在线观看 | 日本妇女高清一区二区三区| 成人无码av免费网站| 三级特黄60分钟在线观看| 百合av一区二区三区| 亚洲黑寡妇黄色一级片| 一本色道久久婷婷日韩| 草草浮力地址线路①屁屁影院 | 中文字幕在线亚洲日韩6页| 亚洲AⅤ无码日韩AV中文AV伦| 日韩有码中文字幕av| 极品尤物精品在线观看| 免费人成网ww555kkk在线| 精品第一页| 久久深夜中文字幕高清中文| 久久久极品少妇刺激呻吟网站| 少妇无码av无码专区| 少妇无码av无码去区钱| 亚洲一区二区三区资源| 国产精品亚洲精品日韩已方| 使劲快高潮了国语对白在线| 亚州AV成人无码久久精品| 亚洲综合久久精品少妇av| 国产不卡视频一区二区三区| 国产成人+亚洲欧洲+综合| 国产人成在线成免费视频| 精品人妻中文av一区二区三区| 区二区三区玖玖玖| 亚洲动漫成人一区二区| 日本91一区二区不卡| 久久99国产精品久久| 国产精品香蕉在线观看| 台湾佬中文偷拍亚洲综合| 中文字幕本久久精品一区| 四虎国产精品免费久久| 骚片av蜜桃精品一区| 蜜桃传媒免费在线观看| 国产va免费精品高清在线观看 |