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        211248 Risk factors for occult nodal metastasis in patients with stageⅠA peripheral non-small cell lung cancer

        2011-08-15 00:54:32JinLuming金璐明DeptThiracSurgPeopHospPekingUnivBeijing100044ChinThoracCardiovascSurg201127212214
        外科研究與新技術(shù) 2011年3期

        /Jin Luming(金璐明,Dept Thirac Surg,Peop Hosp,Peking Univ,Beijing 100044)…∥Chin J Thorac Cardiovasc Surg.-2011,27(4).-212 ~214

        ObjectiveTo study the risk factors of mediastinal lymph node metastasis in patients with≤3 cm peripheral non-small cell lung cancer.MethodsFrom January 2000 to December 2010,a total of 281 patients with NSCLC [152 men and 129 women,aged(60.31 ±12.13)years;≤ 3 cm in diameter]underwent lobectomy or partial resection with systematic mediastinal lymphadenectomy in hospital.Clinical data included age,gender,symptoms,history and quantity of smoking history,history of tumor,family history of tumor,site,diameter,calcification,speculation,border,lobulation,traction of pleural,vascular convergence sign,cavity were collected compaired and analyzed.Single and multi-variate analysis was performed to determine the independent risk of occult N2 nodal involvement.ResultsLogistic regression analysis showes seven clinical characteristics(fleshless(OR:22.262),history of tumor(OR:5.485),diameter(0R:3.788),density(OR;5.850),traction of pleural(OR:1.371),border(OR:8.259)and cavity(OR:7.124)were risk factors.ConclusionFleshless,history of tumor,diameter,density,traction of pleural and the border and cavity were independent predictors of malignancy in patients with≤3 cm peripheral non-small cell lung cancer.13 refs,2 tabs.

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